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Accelerating the Development of Biomarkers for Drug Safety
Language: en
Pages: 101
Authors: Institute of Medicine
Categories: Medical
Type: BOOK - Published: 2009-07-20 - Publisher: National Academies Press

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Biomarkers can be defined as indicators of any biologic state, and they are central to the future of medicine. As the cost of developing drugs has risen in rece
Improving and Accelerating Therapeutic Development for Nervous System Disorders
Language: en
Pages: 107
Authors: Institute of Medicine
Categories: Medical
Type: BOOK - Published: 2014-02-06 - Publisher: National Academies Press

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Improving and Accelerating Therapeutic Development for Nervous System Disorders is the summary of a workshop convened by the IOM Forum on Neuroscience and Nervo
Rare Diseases and Orphan Products
Language: en
Pages: 442
Authors: Institute of Medicine
Categories: Medical
Type: BOOK - Published: 2011-04-03 - Publisher: National Academies Press

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Rare diseases collectively affect millions of Americans of all ages, but developing drugs and medical devices to prevent, diagnose, and treat these conditions i
Evaluation of Biomarkers and Surrogate Endpoints in Chronic Disease
Language: en
Pages: 335
Authors: Institute of Medicine
Categories: Medical
Type: BOOK - Published: 2010-06-25 - Publisher: National Academies Press

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Many people naturally assume that the claims made for foods and nutritional supplements have the same degree of scientific grounding as those for medication, bu
The Drug Development Paradigm in Oncology
Language: en
Pages: 145
Authors: National Academies of Sciences, Engineering, and Medicine
Categories: Medical
Type: BOOK - Published: 2018-02-12 - Publisher: National Academies Press

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Advances in cancer research have led to an improved understanding of the molecular mechanisms underpinning the development of cancer and how the immune system r