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This book provides an up-to-date review of the general principles of and techniques for confirmatory adaptive designs. Confirmatory adaptive designs are a gener
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Type: BOOK - Published: 2011-12-01 - Publisher: CRC Press
With new statistical and scientific issues arising in adaptive clinical trial design, including the U.S. FDA's recent draft guidance, a new edition of one of th
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Type: BOOK - Published: 2016-06-01 - Publisher: Springer
This book focuses on group sequential methods for clinical trials with co-primary endpoints based on the decision-making frameworks for: (1) rejecting the null