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The MYC gene family plays essential roles in normal development and in multiple cellular functions. Moreover aberrant MYC gene activation is profoundly involved
The Heterogeneity of Cancer Metabolism
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Genetic alterations in cancer, in addition to being the fundamental drivers of tumorigenesis, can give rise to a variety of metabolic adaptations that allow can
The Molecular Basis of Cancer
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Authors: John Mendelsohn
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Successfully fighting cancer starts with understanding how it begins. This thoroughly revised 3rd Edition explores the scientific basis for our current understa
Mitochondria and Cancer
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Nearly a century of scientific research has revealed that mitochondrial dysfunction is one of the most common and consistent phenotypes of cancer cells. A numbe
The Myc/Max/Mad Transcription Factor Network
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Scientists often look askance at their colleagues whose research appears too strongly focused on a single gene or gene product. We are supposed to be interested