MYC and the Pathway to Cancer

MYC and the Pathway to Cancer
Author :
Publisher : Cold Spring Harbor Perspective
Total Pages : 0
Release :
ISBN-10 : 1621820084
ISBN-13 : 9781621820086
Rating : 4/5 (086 Downloads)

Book Synopsis MYC and the Pathway to Cancer by : Chi V. Dang

Download or read book MYC and the Pathway to Cancer written by Chi V. Dang and published by Cold Spring Harbor Perspective. This book was released on 2014 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The MYC gene family plays essential roles in normal development and in multiple cellular functions. Moreover aberrant MYC gene activation is profoundly involved in the etiology of a wide range of cancers. MYC encodes a transcriptional regulator that modulates expression of genes controlling cell growth, proliferation, metabolism, differentiation, and death. Deregulation of these expression programs has been linked to MYC's function in tumor initiation, progression, and survival. Written and edited by experts in the field, this collection from Cold Spring Harbor Perspectives in Medicine covers all aspects of MYC biology. The contributors discuss its normal functions in the control of cell growth, cell competition, pluripotency, and development, as well as the molecular basis for the effects of the MYC protein on transcription. In addition, they examine how MYC interacts with other proteins, induces apoptosis, and impacts metabolism, genomic stability, and microRNA expression. The authors also provide a detailed analysis of the role of MYC in tumor initiation and progression. Its involvement in cancers such as medulloblastoma, neuroblastoma, and Burkitt's lymphoma is examined, as are the prospects for anti-MYC therapies in cancer treatment. This book is essential reading for all cancer biologists, as well as researchers studying the regulation of gene expression.

MYC and the Pathway to Cancer Related Books

MYC and the Pathway to Cancer
Language: en
Pages: 0
Authors: Chi V. Dang
Categories: Medical
Type: BOOK - Published: 2014 - Publisher: Cold Spring Harbor Perspective

GET EBOOK

The MYC gene family plays essential roles in normal development and in multiple cellular functions. Moreover aberrant MYC gene activation is profoundly involved
The Heterogeneity of Cancer Metabolism
Language: en
Pages: 186
Authors: Anne Le
Categories: Medical
Type: BOOK - Published: 2018-06-26 - Publisher: Springer

GET EBOOK

Genetic alterations in cancer, in addition to being the fundamental drivers of tumorigenesis, can give rise to a variety of metabolic adaptations that allow can
The Molecular Basis of Cancer
Language: en
Pages: 1948
Authors: John Mendelsohn
Categories: Medical
Type: BOOK - Published: 2008-04-01 - Publisher: Elsevier Health Sciences

GET EBOOK

Successfully fighting cancer starts with understanding how it begins. This thoroughly revised 3rd Edition explores the scientific basis for our current understa
Mitochondria and Cancer
Language: en
Pages: 294
Authors: Keshav Singh
Categories: Medical
Type: BOOK - Published: 2009-04-05 - Publisher: Springer Science & Business Media

GET EBOOK

Nearly a century of scientific research has revealed that mitochondrial dysfunction is one of the most common and consistent phenotypes of cancer cells. A numbe
Systems Biology of Cancer
Language: en
Pages: 597
Authors: Sam Thiagalingam
Categories: Mathematics
Type: BOOK - Published: 2015-04-09 - Publisher: Cambridge University Press

GET EBOOK

An overview of the current systems biology-based knowledge and the experimental approaches for deciphering the biological basis of cancer.