Download or read book What you need to know about an Evolutionary Technique of “Mitochondrial Replacement Therapy(MRT)” a.k.a. “Mitochondrial Donation technique”: A Concise Review. written by Dr. Hakim. K. Saboowala and published by Dr.Hakim Saboowala. This book was released on with total page 46 pages. Available in PDF, EPUB and Kindle. Book excerpt: What you need to know about an Evolutionary Technique of “Mitochondrial Replacement Therapy(MRT)” a.k.a. “Mitochondrial Donation technique”: A Concise Review. Mitochondrial Replacement Therapy also referred to as “Mitochondrial Donation technique” pertains to the category of techniques in which the embryo possessing the nuclear DNA of the parents is subjected to the IVF procedure to have mitochondrial DNA of the donor female. In this era of advanced scientific technologies, MRT aims to treat the infecundity of the diseased females and provide them a suitable chance to have biologically related healthy offspring Mitochondrial replacement therapy (MRT) is a new form of reproductive in vitro fertilization (IVF) which works on the principle of replacing a women's abnormal mitochondrial DNA (mt-DNA) with the donor's healthy one. MRT include different techniques like: § Spindles transfer (ST), § Pronuclear transfer (PNT) or § Polar body transfer (PBT). Transmission of defective mitochondrial DNA to the next generation can also be prevented by using these approaches. The development of healthy baby free from genetic disorders and to terminate the lethal mitochondrial disorders are the chief motive of this technique. However, moral, social, and cultural objections have restricted its exploration. Therefore, it is attempted in this E-Booklet to summarize: · The various methods involved in MRT, · The global status, and · The exaggerated censure over the years which depicts a strong emphasis for social acceptance and clinical application in the world of medical science along with few relevant Illustrations for better understanding the subject at Molecular Level. …Dr. H. K. Saboowala. M.B.(Bom) .M.R.S.H.(London)